American Gods is my favourite of Gaiman's novels, so I definitely recommend it. Like the others said, it's very dense, but Gaiman writes absolutely gorgeous prose. And I don't think it's a problem that you don't usually like fantasy because I'd argue that at their core, Gaiman's books are only marginally more fantastic than, say, Hannibal :)

(which is why I think that Gaiman and Fuller are a perfect match, and based on the trailer that really does seem to be the case)