I don't disagree that changing gender is something that their species evidently is physically capable of, I suppose that I'm just questioning whether or not it feels right for the Doctor. I'm not necessarily arguing that he HAS to stay a man and that it's such an essential part of his identity, but to me him being a man does still play a part in the character that DW has established, and so it would be jarring if his next regeneration was as a woman when he has chosen to regenate as a man 12 times (and was presumedly born male with William Hurtnall as the original version). I do agree on a lot depending on casting if they ever do go with a female doctor, they could probably get me on-board fairly quickly with the right actress, it's just not something that I am picturing otherwise

Sorry if this seems nit picky, but I don't consider the Comic Relief spoof to be canon with the TV series. Missy is the only in-show example of a Time Lord switching gender (and The Doctor's Wife apparently, but I need to rewatch that episode because I can talk about that!), and so I did consider that fairly unusual when judged alongside how other established characters have never switched gender, in spite of some of them regenerating quite a few times